Friday, February 21, 2014

(Re)Mind the Gap

We were pleasantly surprised to find out that BSL postdoc Kristian Valen-Sendstad's paper in press with AJNR, "Mind the gap: Impact of CFD solution strategy on prediction of intracranial aneurysm hemodynamics and rupture status indicators", is the subject of a commentary -- all the more surprising because  AJNR wasn't too keen on the paper when it was first submitted :-)  Way to go Kristian!

Monday, December 30, 2013

Monday, December 23, 2013

Paper Published: Carotid Bifurcation Geometry Is an Independent Predictor of Early Wall Thickening at the Carotid Bulb

This paper, just published online by Stroke, is the culmination of nearly a decade's worth of effort (e.g., see herehere, here, and here) trying to answer a deceptively simple question: can carotid bifurcation geometry be considered an additional risk factor for atherosclerosis.

As it turns out, the answer is "yes, but".  "Yes", because we did tease out a significant and independent association between early wall thickening and bifurcation flare & curvature geometric parameters; "but", because the association was relatively weak.

An equally interesting aspect of the study was the care we had to take to exclude secondary effects of thickening on geometry.  Had we not done so -- and as we showed -- the associations would have been even weaker or, worse, significantly stronger but inverse to what they should have been.